Gene |
Function |
Syndrome/Disease |
n-myc |
oncogene |
neuroblastoma, small cell carcinoma of lung |
L-myc |
oncogene |
Small Cell Lung Cancer |
c-myc |
oncogene |
Burkitt's Lymphoma (Chromosome 8) |
ABL |
oncogene |
CML and ALL |
BCR-ABL t(9;22) |
oncogene |
CML or ALL |
BRAF |
oncogene |
Melanoma |
BCL-2 |
oncogene |
Follicular Lymphoma with t(14;18) |
SIS |
oncogene |
Astrocytoma, Hepatocellular Carcinoma |
HER-1 |
oncogene |
Squamous Cell Carcinoma |
HER-2 |
oncogene |
Breast Cancer, Ovarian Cancer |
KRAS |
oncogene |
Lung Cancer, Colon Cancer, Pancreatic Cancer |
HRAS |
oncogene |
Renal Cell Cancer, Bladder Cancer |
TGFA SIS |
oncogene |
Astrocytoma, Hepatocellular Carcinoma |
APC/β Catenin |
anti-oncogene |
Stomach Cancer, Colon, Pancreatic Cancer, Familial Adenomatous Polyposis |
DCC |
anti-oncogene |
Colon Cancer |
NF1 |
anti-oncogene |
Neuroblastoma, Neurofibromatosis Type 1, Sarcoma |
VHL |
anti-oncogene |
Von Hippel Lindau Syndrome, Renal Cell Cancer |
WT-1 |
anti-oncogene |
Wilms Tumor |
BRCA1, BRCA2 |
anti-oncogene |
Breast Cancer, Ovarian Cancer |
RB |
anti-oncogene, suppresses G1 to S |
inactivated in many cancers |
TP53 |
anti-oncogene p53 "guardian of the cell" |
inactivated in many cancers |
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