Diagnose Meningitis on PE with tests:
Kernig: flex thigh and knee to 90 degrees. Wont be able to fully extend knee.
Bruzinski (1) Neck: curling neck painful and elicits thigh flexion. (2) cheek: pressing cheek elicits elbow flexion. (3) Symphyseal: pubic pressure elicits thigh flexion and abduction.
Diagnose Meningitis gold with Brain MRI
Diagnose Viral vs. Bacterial vs. Fungal with Lumbar Puncture.
Viral: elevated protein (norm: 15-45)
Bacterial: reduced glucose (norm: 50-75)
Fungal: elevated lymphocytes
Causes: Often fecal-oral spread, usually hematogenous. (sometimes resp)
85% caused by enteroviruses: Echovirus, Coxsackie A, B, assoc: rash, pharyngitis, pericrditis, pleurodynia
Also, Echoviruses 70, 71. May cause GBS = Guillain Barre
5% Arboviruses: St. Louis Encephalitis, West Nile, although encephalitis more common.
Also, Mumps causes 10-20% of VM cases in unvaccinated populations.
4% of cases are Herpes viruses. Acyclovir early tx can help. Most often HSV-2
5-10% of HIV+ pts get viral meningitis.
Tx of viral meningitis: analgesics w Acyclovir 750 IV q8 x 14 d just in case it's a Herpes virus. Otherwise self limiting.
Other causes of "aseptic" meningitis include TB-, Mycoplasma-, Fungal- and Lyme Dz-caused.
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