NOTE: During OBGYN rotation, told NOT to use fluconazole for candidal vaginitis, but Gynazole (butoconazole) or Terazol (terconazole) vaginal creams, due to resistance.
Dimorphic: mold in heat/yeast in cold EXCEPTION! |
Immunocompromised at greater risk |
Catalase positive (Cat) |
Forms germ tubes=true hyphae at 37 degrees F. (37 different flavors with germ-tube-mold looking cones) |
Diaper rash (Crying baby) |
Rx for oral/esophageal: Nystatin (binds ergosterol) (Play Nyce!) |
Rx for amphotericin (binds ergosterol) resistance: caspofungin (cell-wall) |
At 20 degrees, yeast form with pseudohyphae (Snowballs with pseudohyphae-looking plant) |
Inhaled steroids are risk factor for oral infection (boy has inhaler) |
Esophageal candidiasis diagnostic for AIDS |
White fungal patches CAN be scraped off (unlike EBV-caused hairy leukoplakia) (KOH salt for shovelling, scraping snow) |
Dx with KOH preparation, microscopy (look for pseudohyphae) |
Antibiotics, birth control, diabetes risk factors for vaginal candidiasis (vaginal candidiasis) |
Rx for local infections: -conazoles (pine cones) |
pH remains normal below 4 with vaginal candidiasis (park open til 4pm) whereas with Gardnerella, it goes above 4. |
At risk of oral/esophageal candida when CD4 count is < 100 (slide with white snow, 100lb wt limit) |
Candidal endocarditis on tricuspid valves for IV drug users (Hearts on the 3 rooftops of the playground) |
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