Tissue Nematodes

Wucheria bancroftii = Witch Spread: moquito vector, common in Africa Eosinophilia = pink marbles Organisms seen on thick blood smear =blood on hat Cough from filiariae in lungs Lymphadenopathy = puffed sleeves Rx: Diethylcarbamazine = magazine Elephantiasis from long-standing lymphedema = Elephant-like legs
Dracunculus medinensis Spread by water with Copepods containing larvae Adult females spread from painful skin ulcer
L. Loa Deer flies vector Adult worms migrate across conjunctiva Rx: diethylcarbamazine, or albendazole Local subcutaneous swellings Eosinophilia
Onchocerca volvulus Black fly vector Rx: Ivermectin microfilariae seen in skin biopsy under microscope Microfilariae seen in eye and can cause blindness Hypo and Hyperpigmented spots in onchodermatitis Eosinophilia Toxocara canis Ocular larva migrans lead to blindness Transmitted by consuming food containing dog and cat feces Rx: Albendazole Eosinophilia