Tuesday, November 8, 2016

Clostridium perfringens





Spores found in soil
Causes gas gangrene
Infections associated with wounds
Obligate anaerobe
Alpha-toxin = lecithinase causes myonecrosis, disrupts cell membranes
Red cell hemolysis
Gas gangrene
Double zone of hemolysis
Rx: IV Penicillin G
Slow onset watery diarrhea from spore ingestion

commonly C. perfringens and flesh eating bacteria

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