Tuesday, November 8, 2016

Clostridium tetani





Risus sardonicus smile (smiling Rhesus Monkey)
Rigid paralysis
Spores Transmitted by rusty objects, dirt (Spores and dirt, nails, barbed wire around lab cage)
Obligate anaerobe (gas mask)
Gram Positive (Purple color) rod
Oposthotonuss: exaggerated extension and arching of back (background monkey in this position)
Tetanospasmin Toxin cleaves SNARE protein  (Snares being cut)
Acts as a protease (Scissors)
Inhibits release of GABA and Glycine inhibitory neurotransmitters (G&G Labs)
Targets Renshaw Cells, inhibitory interneurons (Wrenches and saws)
Retrograde Transport
Toxoid vaccine (Researcher is holding it)

Commonly Tetanus and C. tetani and lock jaw lock-jaw

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