Tuesday, November 8, 2016

Streptococcus pneumoniae and viridans




Alpha-hemolytic
S. pneumoniae
Encapsulated with polysacharride
Optochin sensitive 
Lancet-shaped gram positive diplococci
Bile soluble
Rust colored sputum in lobar pneumonia
MOPS: Meningitis, Otitis Media, Pneumonia, Sinusitis (most common bacterial cause of each)
IgA protease
Sickle cell patients susceptible
Rx: Macrolide, erythromycin, 60S subunit
Rx: Ceftriaxone
23 valent adult vaccine: only IgM response
7 valent childrens vaccine: IgG response (long-lasting immunity)
S. viridans
Optochin resistant
Bile resistant
Dental caries (especially Strep. mutans)
Worsens previous valve damage, Mitral valve prolapse, most likely to be damaged
Adheres to Platelets, using dextrans glue synthesized from glucose 
No capsule

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